Cart
sales@molnova.com
Resolvin D1
CAS No. 872993-05-0
Resolvin D1( —— )
Catalog No. M33232 CAS No. 872993-05-0
Resolvin D1 (RvD1) is an endogenous pro-inflammatory mediator that blocks pro-inflammatory neutrophil migration by regulating actin polymerization.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameResolvin D1
-
NoteResearch use only, not for human use.
-
Brief DescriptionResolvin D1 (RvD1) is an endogenous pro-inflammatory mediator that blocks pro-inflammatory neutrophil migration by regulating actin polymerization.
-
DescriptionResolvin D1 (RvD1), an endogenous pro-resolving mediator of inflammation, is derived from omega-3 docosahexaenoic acid during the resolution phase of acute inflammation. Resolvin D1 blocks proinflammatory neutrophil migration by regulating actin polymerization, reduces TNF-α–mediated inflammation in macrophages, and enhances phagocytosis of apoptotic cells by macrophages.
-
In Vitro——
-
In VivoAnimal Model:18-20?g thirty 8-week-old female DBA/1J mice (collagen antibody-induced arthritis (CAIA))Dosage:100, 500, and 1000?ng (or 1000 ng, daily on days 4-10)Administration:i.p. injection; daily on days 10Result:Exhibit a reduced arthritic score.
-
Synonyms——
-
PathwayApoptosis
-
TargetApoptosis
-
RecptorApoptosis
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number872993-05-0
-
Formula Weight376.49
-
Molecular FormulaC22H32O5
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES[C@@H]([C@@H](/C=C/C=C/C=C\C=C\[C@H](C/C=C\CC)O)O)(C/C=C\CCC(O)=O)O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Schmid M, et al. Resolvin D1 Polarizes Primary Human Macrophages toward a Proresolution Phenotype through GPR32. J Immunol. 2016 Apr 15;196(8):3429-37.?
molnova catalog
related products
-
5-Benzylidene-3-ethy...
5-Benzylidene-3-ethyl rhodanine(BTR-1) is an active anti-cancer agent. BTR-1 activates apoptosis and induces cell death.
-
(-)-Perillyl Alcohol
(S)-(?)-Perillyl alcohol a monoterpene found in lavender inhibits the farnesylation of Ras upregulates the mannose-6-phosphate receptor and induces apoptosis. It also has anti-cancer activity.
-
Anticancer agent 110
Anticancer Agent 110 exhibits potent in vitro anti-leukemia activity, demonstrating high cytotoxicity against K-562 lineage chronic myelogenous leukemia cells at nanomolar concentrations.
